The term Myeloproliferative Neoplasms (MPNs) refers to a group of blood tumors characterized by an overproduction of blood cells. This classification includes Chronic Myeloid Leukemia (CML), Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (MF).

These diseases are caused by mutations that promote the proliferation, differentiation, and survival of blood cells. The clinical manifestations of these diseases are different and range from mild symptoms such as weakness and fever to more severe events such as thrombosis or progression. Diagnosis can be made through blood tests and tests that can identify the mutations responsible for the disease.